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Investigating how DNA damage responses combat infections by the typhoid pathogen Salmonella enterica
toxin a tumour suppressor mechanism called senescence. A major virulence factor implicated in typhoid is the typhoid toxin of Salmonella Typhi. We discovered that the toxin induces DNA damage responses in
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Exploring the therapeutic potential of a novel Botulinum toxin School of Biosciences PhD Research Project Self Funded Prof A Peden, Prof Jason King Application Deadline: Applications accepted all
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo
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of uraemic toxins, inflammation and impaired muscle function (sarcopenia). Thus, the microbiota emerges as a key player and a potential therapeutic target. The main objective of this PhD thesis is to assess
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novel, disruptive dialyser design. Directly supervised by Professor Pierre Ricco, you will be responsible for the theoretical analysis and numerical simulations of blood and dialysate flows and toxin
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plant resistance against turfgrass pests and diseases; Evaluating the impact of bacterial toxins on insect pests and diseases infesting pecan and turfgrass and non-target effects; Assisting with pest
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, multimodal treatment plans incorporating pharmacologic therapies (topical anesthetics, neuromodulating medications, hormonal therapies), trigger point injections, pudendal nerve blocks, and botulinum toxin
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thinking is key to success with the needs patients and families. Spasticity management with the use of toxin delivery via injections, working through a team approach method, teaching closely with the MD
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disorders, DBS and botulinum toxin. Unless determined otherwise, each of these experiences will be staffed by an attending neurologist in order to provide appropriate supervision. Additional clinical
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and botulinum toxin. Unless determined otherwise, each of these experiences will be staffed by an attending neurologist in order to provide appropriate supervision. Additional clinical experiences