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tissue using genetic mouse models, functional screens, and single cell and spatial omics technologies. More details about the laboratory: https://www.ibt.cas.cz/en/research-laboratories/laboratory
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tissue using genetic mouse models, functional screens, and single cell and spatial omics technologies. More details about the laboratory: https://www.ibt.cas.cz/en/research-laboratories/laboratory
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within the cell microenvironment, impact cellular machinery. Our current research focuses on physical modulation of organelle networks to control cell fate in cancer and regeneration. Our lab pioneers
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journals, including Cell Metabolism, Nature Metabolism, Cancer Cell and Cancer Research, to name a few. More detail about the laboratory see https://www.ibt.cas.cz/en/research-laboratories/laboratory
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Biology We investigate the mechanisms underpinning DNA damage and cancerogenesis, with a focus on: Replication Stress & Genome Instability: How oxidative stress in cancer cells leads to formation