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to determine why defects in intracellular transport cause neurodegenerative diseases. They use a combination of approaches including protein biochemistry and in vitro reconstitution, single-molecule biophysics
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they continue to investigate. Approaches include genetics, spatial genomics, single-molecule biophysics, super-resolution imaging, computational modeling, and structural studies including X-ray
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, biochemistry, single molecule imaging, and we have enhanced these efforts using large-scale structure prediction using AlphaFold (predictomes.org). The Walter lab is a welcoming community where all members
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biology – pioneering single-molecule techniques to investigate the mechanics and topology of fundamental DNA processes and theoretically modeling these processes using statistical mechanics and
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wide range of approaches: protein biochemistry and reconstitution, single-molecule biophysics, proteomics, metabolomics, fungal genetics, evolutionary analysis, mammalian cell culture, and live-cell