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! The sensing technologies that are being developed in the Molecular Biosensing group (MBx, see www.tue.nl/mbx ) are unique in the world. The sensors are based on reversible single-molecule interactions
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-ray Free-Electron Lasers (XFEL)-driven molecules”. Project: The goal will be to significantly advance the state of the art in theoretical and computational techniques in order to investigate coherent
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& Molecular System group employs single-molecule techniques, AFM and optical tweezers, to study the operation of small synthetic molecules and biomolecules. Our expertise covers the development of single
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to counteract the SARS-CoV-2 pandemic it has become increasingly clear that RNA is on the verge of becoming another major molecule class for the fields of diagnostics, prevention and treatment of diseases. Funded
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these, Nucleotide-binding, Leucine-rich-Repeat proteins (NLRs) constitute a large family of intracellular receptors of pathogen-associated molecules, termed effectors. To restrict infection, NLRs trigger a response
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matter’ of biology, under-studied owing to the historical lack of preparative and analytical tools to probe the local molecular composition and transient interactions of molecules within glycocalyces, and
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the verge of becoming another major molecule class for the fields of diagnostics, prevention and treatment of diseases. Funded by the Elite Network of Bavaria (ENB), the graduate programme RNAmed takes a
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.-Investigating interactions with lipid bilayers and vesicles.-Observing motor motion and evaluating performance with single-molecule localisation fluorescence microscopy. We are looking for candidates who have:-A
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valorisation process, performing the following tasks: - Implementation and execution of functional assays to test the efficacy, toxicity and oral absorption of small molecules or biologics in preclinical
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. Our research combines computational chemistry, cheminformatics, bioinformatic and AI to design new molecules and enzymes for unprecedented catalytic functions. In this project, you will: Develop