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Field
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organic methods for functional small molecules and polymers. The goal of projects in the Huang lab is to tackle critical societal challenges through precise structural control, efficient manufacturing, and
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organic methods for functional small molecules and polymers. The goal of projects in the Huang lab is to tackle critical societal challenges through precise structural control, efficient manufacturing, and
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31841BR Molecular Biosciences Position Overview The Holmstrom Lab at the University of Kansas invites qualified candidates to submit applications for the position of Single-Molecule Biophysics
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integrating statistical-mechanical theory, quantitative modeling, and experimental single-molecule methods. We aim to develop mechanistic models of receptor activation that combine physical theory with data
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of splicing regulation using an array of state of the art biophysical, structural, molecular and chemical biology techniques, including single molecule analyses of splicing complexes as pioneered by
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. Our lab applies advanced structural and biophysical methodologies including cryo‑electron microscopy (cryo‑EM), X‑ray crystallography, single‑molecule fluorescence, and enzyme kinetics to elucidate how
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of the metalloprotease ADAM10 trafficking by tetraspanins in colon cancer, using single-molecule techniques. - Single-molecule biophysics (single-molecule localization microscopies and single-molecule Förster Resonance
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lifetime microscopy and single-molecule localization microscopy, with the aim of enabling dynamic observation of living biological systems and nanostructures. This research lies at the interface of physics
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decide the fate of their RNAs - whether to translate, store, or degrade them. Using biochemical reconstitution, fluorescent labeling, and single-molecule imaging, you will explore how molecular machines
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responsible for designing, building, and utilizing single-walled carbon nanotube field effect transistor (SWNT FET) sensors to probe biological phenomena at the single-molecule level. See Turvey et al. (2022