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early-warning signals and tipping points relevant to the PlanetaryBoundaries framework . Complementing this, work package 2 addresses marine biodiversity, ecosystem health, and biosphere functioning by
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research on memory and behavior is how the brain responds to environmental stimuli, and a major challenge here is the heterogeneity of cell-signaling pathways, brain cells and neural networks. We study
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ubiquitylation (http://www.ppu.mrc.ac.uk/). Many world-leading researchers in the field of signal transduction have trained within the MRC PPU. The major aims of the MRC PPU are to advance understanding
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signaling models”. The scholarship is full-time for 2 years, with access starting in May 2026 or by agreement. The research will be carried out in the laboratory of Cemal Erdem at the Department of Medical
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and downstream signaling pathway components. The candidate is expected to be able to work independently and to supervise students in the group. Experience with protein purification, bacterial and insect
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Job Description We are seeking a postdoctoral fellow to investigate LRRK2 signaling pathways in healthy and Parkinson's disease (PD) conditions. LRRK2 is a major genetic risk factor for PD and a
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leftward flow in the left–right organizer (LRO), but the identity and mechanism of the flow-transported symmetry-breaking cue has long remained elusive. Defects in this process are a major cause of
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determination of AIS constituents and their adaptation to axo-axonic synapses Mechanistic/biophysical models for synaptic interactions with action potential signals generated at AIS Examples of other tasks
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to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across
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focuses on the resilience of the marine sinks of heat and carbon, using Earth system and biogeochemical models, observational data, and scenario analysis to identify early-warning signals and tipping points