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-fate determination, genome editing, the role of chromosome structure and chromatin modification in gene regulation, and the molecular evolution of chromosome-wide mechanisms of gene control in
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Description Biomolecular condensates have emerged as a new paradigm to understand biological functions in living cells. Dresden has pioneered research in the field of biomolecular condensates and
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Postdoctoral position to study Polo kinase and centrosome abnormalities in cancer and other diseases
approaches (e.g., super-resolution imaging, single molecule tracking, in vitro reconstitution, X-ray crystallography, and cryo-EM) to delineate the molecular bases and structural rules governing
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data in neurogenetic syndromes (including sex chromosome aneuploidies) to map effects of altered gene dosage on human brain organization. There will be a special emphasis on: use and construction
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to uncover the molecular mechanisms driving sex differences in cardiac physiology that underlie pronounced sex biases in heart disease. We focus on biological sex—the combined effects of sex chromosomes and
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, examining gene expression and its regulation. It formulates an overall picture of cell interactions within organisms. Start of studies in the winter semester (October) Opening of applications and publication
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on the structure–function relationship of the bacterial chromosome. How bacteria organize their DNA and how this structure influences gene expression remain open questions. For example: How is the chromosome
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strategy (PMIDs: 29123070, 33621493, 33087936, 30566856, 39947938; doi: https://doi.org/10.1101/2025.03.15.641049 ). Postdoctoral Projects Project 1: Replisome Dynamics, Replication Stress, and Cancer
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biomedical engineering, bioinformatics, biotechnology, molecular imaging and biomaterials. Training within the RegSci PhD programme takes place across three levels: students carry out their own research
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, 33621493, 33087936, 30566856, 39947938; doi: https://doi.org/10.1101/2025.03.15.641049 ). Postdoctoral Projects Project 1: Replisome Dynamics, Replication Stress, and Cancer Vulnerabilities This project aims