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/suspension, ants, C. elegans, Drosophila, zebrafish, and mice, using conventional chemical fixation, microwave techniques, high-pressure freezing, and freeze-substitution. We offer semi-thin and ultra-thin
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, biochemical, and genetic approaches. To accomplish these aims, the incumbent will work with a range of model organisms and cultured cell systems, including C. elegans, D. melanogaster, HEK cells, and HeLa cells
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on autophagy enhancer drugs. This work has been informed by a novel C. elegans model of antitrypsin deficiency that has been adapted to high-content screening of drug and RNAi libraries for new therapies
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are seeking motivated individual to join my research group to study the functions of DPPIV family proteases using C. elegans as a model system. Our long-term goal is to understand how these proteases regulate
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for the model nematodes C. elegans and C. remanei . Associated projects entail CRISPR/Cas9 genetic engineering, experimental evolution, genomics, and field sampling. The selected candidate will also mentor
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C. elegans and its natural parasites. Associated projects entail evolve-and-resequencing, quantitative trait mapping, and field sampling with spatial analyses. The selected candidate will also mentor
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zebrafish, mouse, C. elegans, and more recently humans. This is a novel and quickly developing field of research where many open questions remain to be addressed including 1) the nature and trafficking
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Specialist A Job Profile Title Research Specialist A Job Description Summary This is a full time (40 hours per week) research specialist position to assist in experiments to study sleep in the round worm C
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Independently conduct molecular cloning, mutagenesis, protein purification, protein characterization, protein engineering and design, enzyme kinetics, protein crystallization. Microbiology assays, including C
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cells Single-molecule dissection of ciliary membrane protein entry in C. elegans sensory neurons Structural and functional characterization of plectin inhibition in liver cancer Studying R-loop formation