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murine microenvironments and use high-resolution spatial omics techniques to prioritize molecular factors that may drive the immune cell states. These will then be validated through in vivo screening
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on the University Hospital Campus Gasthuisberg, where it hosts about 230 researchers and staff, creating a vibrant ecosystem where fundamental research meets clinical practice. What we do Our cells continuously
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ample opportunities for direct validation in biologically relevant settings. This interdisciplinary atmosphere has been a main catalyst for many past successes: https://europepmc.org/article/MED/35021063
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function of disease-relevant circuits and eventually use this knowledge to stratify Parkinson’s disease; and 2) running CRISPR screens on hiPSC-derived neurons and glia to disentangle the complex genetic
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Smet (https://desmetlab.sites.vib.be ) and F. Van Breusegem (https://vanbreusegemlab.sites.vib.be ) have expertise in abiotic stress signaling and in advanced molecular profiling, including mass
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of neurodegenerative disorders. The candidate will approach this by: 1) using advanced Brain-on-Chip models to understand how genetic risk affects the function of disease-relevant circuits and eventually use
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centrosome is essential for early embryonic cell divisions, we still do not understand the profound “centrosome reduction” it undergoes during spermatogenesis and how this pathway impacts embryo development
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machine learning approaches to link gene-regulatory programs to neuronal phenotypes. Use explainable sequence-to-function models to interpret regulatory logic underlying neuronal identity and function
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Work location: Ghent, Leuven, Antwerp, Brussels – multi-site role | Reports to: Managing Directors Employment fraction: 80-100% | Contract: Permanent About VIB VIB is a leading life sciences
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, collaborative environment across VIB- HQ and VIB-Leuven, offering extensive scientific and administrative support. A competitive salary and full employment package. The chance to shape both scientific strategy