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Project Outline: The overarching aim of this study is to assess the clinical utility of blood derived biomarkers such as circulating tumour cells (CTCs), circulating tumour DNA (ctDNA) and extracellular vesicles for predicting and monitoring response to immune checkpoint blockade in melanoma and...
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Project Outline: Over recent years, research has shifted towards studying the impact of modifiable lifestyle factors such as dietary interventions and physical activity on Alzheimer’s Disease risk reduction. In particular, three dietary patterns have been studied with respect to cognitive...
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Project Outline: Increasing the intake of fruits, vegetables and whole grains remains the foundation of dietary approaches to prevent disease. However, surprisingly little is known about the components of these foods that contribute to cognitive health, or the mechanisms involved. Identifying...
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Project Outline: Exercise oncology is the application of exercise medicine for people with cancer. It is well established that higher volumes and intensity of physical activity or exercise reduce overall and cancer specific mortality by up to 60%. Precision exercise oncology reduces the side...
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Project Outline: A global rise in life expectancy comes with an increased burden of serious life-long health issues and the need for useful real-time indicators of the ageing process. We propose to investigate the value of biochemical profiles of lgG N-glycosylation in blood as clinically...
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Project Outline: Stroke is the second commonest cause of death and the sixth leading cause of disease burden globally with an estimated 6.5 million stroke deaths annually, expected to rise to 8 million by 2030 (World Stroke Organisation, 2022). The average stroke destroys roughly two million...
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Project Outline: The project will be situated within a program of research on the prevention of hospital acquired complications and will align with the Australian National Safety and Quality Health Service (NSQHS) Standards and Western Australian Sustainable Health Review that aim to protect the...
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Project Outline: Proper function of the nervous system is vital to allow muscles to contract. Indeed, exercise training results in improved muscle performance. Conversely, with de-training or ageing the loss of strength can result in poor health and physical function. However, the specific...
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Project Outline: The glycome is the entire complement of sugars, whether free or present in more complex molecules, of an organism. An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature. Glycosylation, the...
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Project Outline: This study will examine exposure levels and strategies employed by outdoor workers, such as farmers with high physical work demands, to cope with heat stress. Cohorts from developing countries are of particular interest. Desired skills: Master of Public Health (by...