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-microenvironment-models-and-their-use-to… Where to apply Website https://www.ceitec.eu/lymphoid-microenvironment-models-and-their-use-to-study-t… Requirements Additional Information Work Location(s) Number of offers
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: Computational biophysics, drug delivery, protein design Keywords:Computer simulations, coarse-grained model, molecular dynamics, membrane fusion, fusion protein, protein design Funding of the PhD candidate: ERC
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Overcoming the Endosomal Barrier: Design Principles of Fusogenic Proteins for Lipid Vesicles Annotation: Cancer remains one of the leading causes
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microenvironmental interactions of CLL. We will decipher the molecular functions of these lncRNAs using biochemical and cellular approaches and via a novel lncRNA knock-out mouse model. We have engineered mice
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-in-3d-stem-cell-derived-human-organ-models/t11589 Where to apply Website https://www.ceitec.eu/protein-in-cell-nmr-spectroscopy-in-3d-stem-cell-derived-… Requirements LanguagesENGLISHLevelGood
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the PhD student using technics such as genome editing (CRISPR), RNA sequencing, use of primary samples, functional studies with various in vitro and in vivo mouse models. The research is also relevant
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novel regulators of the B cell survival, proliferation and crosstalk with other immune cells. The PhD student will further investigate this using techniques such as genome editing (CRISPR), RNA sequencing
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
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https://pubmed.ncbi.nlm.nih.gov/36596869/ Research area: Cancer biology Keywords: lymphoma, CLL, lncRNA, microenvironment Funding of the PhD candidate: Part-time salary (min. 0,5 FTE) on EHA grant/AZV