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for up to two academic referees In case of any troubles with the e-application, please contact Petra Linhartová (petra.linhartova@ceitec.muni.cz ). Where to apply Website https://jobrxiv.org/job/phd
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of any troubles with the e-application, please contact Petra Linhartová (petra.linhartova@ceitec.muni.cz ). Where to apply Website https://jobrxiv.org/job/two-phd-candidates-students-in-molecular
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
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. 2012; 24(6):634-9. https://pubmed.ncbi.nlm.nih.gov/22960555/ Research area: Cancer biology Keywords:CLL, microenvironment, CD20, BTK/PI3K inhibitors Funding for the PhD candidate: In the academic year
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the CXCR4/SDF-1 axis. Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1. PMID: 27480113 Free PMC article Kipps et al. Chronic lymphocytic leukaemia. Nat Rev 2017 https
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targets for therapy. Recommended literature: Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA Biol. 2021 May;18(5):619-632. https://pubmed.ncbi.nlm.nih.gov
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practices. The ideal researcher (EU Researcher Profile: R2) profile: Must-have: A PhD degree or equivalent in structural biology, Chemistry, biochemistry, biophysics, or a related field. Expertise in
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and data analysis is desirable. Information about the supervisor: 2 PhD students 2 absolvents Supervisor´s personal webpage https://www.ceitec.eu/dalibor-blazek-ph-d/u25918 Research group info https
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the PhD student using technics such as genome editing (CRISPR), RNA sequencing, use of primary samples, functional studies with various in vitro and in vivo mouse models. The research is also relevant
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets