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. 2012; 24(6):634-9. https://pubmed.ncbi.nlm.nih.gov/22960555/ Research area: Cancer biology Keywords:CLL, microenvironment, CD20, BTK/PI3K inhibitors Funding for the PhD candidate: In the academic year
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to targeted therapy. Recommended literature: Hoferkova E, et al…. Mraz M. Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations
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the PhD student using technics such as genome editing (CRISPR), RNA sequencing, use of primary samples, functional studies with various in vitro and in vivo mouse models. The research is also relevant
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scholarship + CEITEC PhD School scholarship. Requirements on candidates: Motivated smart people that have the “drive” to work independently, but also willing to learn from other people in the lab and
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novel regulators of the B cell survival, proliferation and crosstalk with other immune cells. The PhD student will further investigate this using techniques such as genome editing (CRISPR), RNA sequencing
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
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https://pubmed.ncbi.nlm.nih.gov/36596869/ Research area: Cancer biology Keywords: lymphoma, CLL, lncRNA, microenvironment Funding of the PhD candidate: Part-time salary (min. 0,5 FTE) on EHA grant/AZV