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Field
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stem cells (satellite cells) can be guided by anatomical and environmental signals to generate muscle fibers that are more resistant to disease. Using a unique collection of genetically engineered
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Stein bei N rnberg, Bayern | Germany | about 2 months ago
applications, improving lives. Recently, our Gene Editing group at the Institute of Stem Cell Research developed Synthetic Transfer Vehicles (STVs), a programmable protein-based RNA delivery platform
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instability in human stem cells, disease, and cancer, using human pluripotent stem cells and targeted differentiation approaches as a primary working model. Our goal is to determine how DNA and RNA instability
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to identify candidate disease-causing variants. You will develop model systems, e.g. genome-editing of immune or induced pluripotent stem cells (iPSC) with specific patient-derived genetic variants. We aim
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capable of conducting electrical currents over centimeter distances. Electric currents are channelled via highly conductive protein fibers embedded in the cell envelope. These fibers form a unique
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writing, and disseminate findings through high-impact publications. Profile PhD in neuroscience, immunology, stem cell biology, or related discipline. Proven expertise in Parkinson’s disease models and iPSC
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Heidelberg). The work of our research group (http://lab.mueller-tidow.de ) focuses on stem cells and therapy resistance. We aim to understand how epigenetic dysregulation participates in the pathogenesis and
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mouse embryonic stem cells to allow for rapid protein depletion, mapping transcriptional effects (RNA-seq, TT-seq, PRO-seq), proximity labeling approaches, ChIP, and the bioinformatic analysis
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applying must have a PhD degree in biomedicine, molecular medicine, molecular biology, gene technology, immunology, stem cell biology or a related discipline. Expertise in experimental haematology
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pursue independent projects during their training. The Barefield lab uses mouse models and human induced pluripotent stem cell derived cardiomyocyte models of genetic cardiovascular disease to study