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function of disease-relevant circuits and eventually use this knowledge to stratify Parkinson’s disease; and 2) running CRISPR screens on hiPSC-derived neurons and glia to disentangle the complex genetic
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of neurodegenerative disorders. The candidate will approach this by: 1) using advanced Brain-on-Chip models to understand how genetic risk affects the function of disease-relevant circuits and eventually use
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centrosome is essential for early embryonic cell divisions, we still do not understand the profound “centrosome reduction” it undergoes during spermatogenesis and how this pathway impacts embryo development
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