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laboratories, and other health care organizations. Our operations are based at the University of Washington Medical Center, Harborview Medical Center, South Lake Union, Northwest Hospital and the Seattle Cancer
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channels modulates these pathways. We use mouse models and primary human cells to query immune function in vitro and in vivo. Core experimental techniques include mouse disease models, in vitro functional
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how genetic and environmental factors interactions shape mucosal immunity and metabolism. Our approach includes state-of-the-art multi-omics, novel organoid culture, genetically engineered murine models
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therapies, and disease models, including mutant mice and iPSC-derived neurons to further understand neurodegenerative processes. These projects are funded by multiple grants from the NIH. This opportunity
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, the causative agent of cholera. We perform detailed studies using specimens derived from human samples. Projects include: Creating knock-out mutants to study how V. cholerae virulence is impacted by gut bacteria
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models of sporadic low-grade glioma and Neurofibromatosis Type 1 (NF1)-related optic pathway glioma to accomplish these goals. We are additionally interested in how environmental exposures affect the non
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), Parkinson's disease and other forms of neurodegeneration. We are particularly interested in synaptic injury. We work with animal models (mostly mice) and with patients in the hospital, and collaborate with
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in addition to established cell lines. HIV laboratory research or related virology. Mouse models, including tissue harvesting and in vivo experimental work. CRISPR-based genetic perturbation approaches
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Duties & Responsibilities: Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ . Trains under the supervision of a faculty mentor
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approaches, including in vivo Massively Parallel Reporter Assays (MPRAs), to define the sequence basis and functional consequences of enhancer activity and to expand MPRA-based approaches to other aspects