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evolutionary cell biology. Our ERC-funded project uses pigment cells in tropical cichlid fishes as a powerful model to uncover how complex cellular phenotypes and developmental programs evolve. We integrate
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The McWilliams Lab investigates physiological autophagy, a membrane-driven lysosomal degradation pathway essential for cell, circuit and tissue homeostasis. Impairments in autophagy and lysosomal
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in vivo genetic mouse models, advanced live and intravital imaging, engineered microchip models, primary cell co-culture systems and novel microscopy and analysis methods. The research will provide
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techniques such as mouse models, in vivo immune cell functional assays, flow cytometry, cell biology, metabolic assays, imaging and omics-techniques (next generation sequencing). Applicants should possess a
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the Neuroscience Center in the University of Helsinki (see: https://www2.helsinki.fi/en/researchgroups/synaptic-plasticity-and-development ).The research interests are focused on functional maturation of neuronal