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local activation), multi-timescale adaptation (local memory), and stimulus-specific adaptation (multi-task processing). While the co-optimization of dendrite-inspired functional circuits with emerging
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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 21 days ago
the design and enzymatic synthesis of hypermodified xeno-nucleic acids with a combination of modifications at the base, sugar moiety and phosphate linkages. After optimization of the methodology, hypermodified
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: Establish a tailored enzyme panel for site-selective late-stage functionalization of complex NP scaffolds. Optimize biocatalytic reactions to generate a focused library of new NP analogues. Evaluate
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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 22 days ago
PROTACs for several kinases, which are validated targets in oncology and in CNS disorders. It will be focused on linker optimization, selection of ligase ligands and specificity for target kinase. Our
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* for combinatorial solving; some details can be found below. The field of combinatorial optimization is concerned with developing generic tools that take a declarative problem description and automatically compute
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promising technology for producing large and complex metal component. Although its potential has been widely demonstrated, significant challenges remain in optimizing the process to ensure the quality
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bioprocess optimization. The successful candidate will contribute to the development of sustainable bioconversion platforms for the transformation of biogas-derived carbon into amino acid-enriched biomass
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-temperature performance. The PhD project will focus on the development, investigations and optimizations of new electrode and electrolyte materials. The project will expand the student’s skill set in scientific research
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official guidelines in the link provided: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/wp-call/2023-2024/wp-2-msca-actions_horizon-2023-2024_en.pdf ). The final gross
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project, you will help design, simulate, and optimize these next-generation communities — making clean, local, and intelligent energy systems a practical reality. Your key responsibilities include