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Application deadline: 31/03/2026 Research theme: Biocatalysis and Protein Engineering Centre for Sustainable Synthesis – BioProcess How to apply: https://www.mib.manchester.ac.uk/research/centres
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Romania Specific Requirements Biochemical methods for fractionation of protein complexes and cellular organelles Electrophoretic and chromatographic techniques for biomolecule separation Analysis
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methods for fractionation of protein complexes and cellular organelles Electrophoretic and chromatographic techniques for biomolecule separation Analysis of biomolecules by mass spectrometry
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constitute the building blocks for the biomolecules of life. They are integral components of oligonucleotides that encode the proteins required to control biological processes. Structurally modified
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(heparan sulfate proteoglycans, HSPGs) and a cellular scavenger receptor (low-density lipoprotein receptor-related protein, LRP1) to fine-tune its abundance and function within the retina. These regulatory
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This studentship investigates the axon degeneration protein SARM1, an exciting target for therapy in a wide range of neurological conditions. Knocking out SARM1 protects neurons in a TDP-43
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interactions. We develop and apply chemical biology methods – including chemical probe synthesis, protein biochemistry and chemical proteomics – to understand the impact of bacterial enzymes on multipartite
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techniques to identify the enzymes, as well as protein purification and recombinant protein expression to get hold of the enzymes. The PhD student will be part of the large and international PEP group (https
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neurological and developmental involvement. Peroxisomes generate high levels of hydrogen peroxide in their matrix but lack typical protein repair systems such as those found in other subcellular compartments
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, including cytoskeletal alterations, protein aggregation, protein phase transitions, DNA damage response, transcription stress, epigenetic changes and metabolic alterations, can result as a consequence of