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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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data. We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in vivo during developmental and disease. These technologies are a game-changer in the speed
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role in membrane remodeling. It also aims to deepen the mechanistic understanding of solute transport in ion channels and transporters of medical relevance. We apply state of the art methods
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