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. Our mission is to move beyond descriptive biology and develop predictive, mechanistic models that connect molecular regulation to cellular and systems-level phenotypes. The Laboratory of Computational
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the development of genetic autoinflammatory diseases. Using techniques in cell biology, molecular biology and biophysics you will investigate how loss of function of the RNA editing enzyme ADAR1 causes the human
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Saelens team. Research Project In this research project you will develop probabilistic deep-learning models that automatically extract biological and statistical knowledge from in vivo perturbational omics
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that regulate plant development and physiology, including adaptation to environmental stresses. They are synthesized in the cell interior and exported across the plasma membrane to bind receptors at the cell
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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assemblies in sperm in a near-native state using cryo-ET (‘visual proteomics’), (ii) developing expansion microscopy approaches for robust labeling and higher-throughput mapping of newly identified components
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initiative investigating how human-specific features of brain development shape early behavior and neural circuit function in autism spectrum disorders (ASD). This position is a joint effort between the
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facilities and training in advanced techniques. Opportunities for career development, networking, and mentorship. Support for presenting at international conferences and publishing in peer-reviewed
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to neurodegenerative diseases of the central and peripheral nervous system, with an emphasis on understanding the genetic etiology and developing diagnostics and treatment methods for these diseases. Approaches range