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molecular modeling, optimize their structures for selectivity and tumor retention, and conjugate the most promising candidates to chelators for radiolabeling with ¹⁷⁷Lu or ¹⁶¹Tb. This chemistry-driven project
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to conservative assumptions, costly over-remediation, and sometimes misdirected risk management. This project develops a quantitative Adverse Outcome Pathway (qAOP) toolbox that directly links measurable molecular
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bioconjugation and radiochemistry tools to rigorously evaluate the therapeutic potential of phage-based vectors. Over the four-year timeline, the research will advance from molecular design and phage production
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