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methods for single-cell data analysis (tools developed by the team : https://github.com/cantinilab ). Single-cell high-throughput sequencing, extracting huge amounts molecular data from a cell, is creating
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physiological human colon model, combining patient-derived colonic organoids with organ-on-chip (OoC) and enabling to modulate the key gut environmental cues: mechanical stimulation (peristalsis and shear stress
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approach combining cryo-electron microscopy, NMR spectroscopy, and advanced molecular modeling, the research will unravel the molecular architecture and conformational dynamics of pili and their interactions
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