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Center for Drug Evaluation and Research (CDER) | Silver Spring, Maryland | United States | about 9 hours ago
traditionally relies on a multi-tiered testing strategy to detect anti-drug antibodies (ADAs), involving sequential screening, confirmatory, and titer assays. Recently, the signal-to-noise ratio approach has
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, neoantigens, cytokines, and antibodies; bispecific antibodies; and small-molecule immunomodulators. BioNTech is partnered with several large pharmaceutical companies, including Bristol Myers Squibb, Duality
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, transcriptomics, antibody assays, and advanced 3D microscopy. For this, a lightsheet microscope dedicated to the imaging of cleared samples has been acquired, as well as a workstation for VR-assisted image analysis
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Center for Drug Evaluation and Research (CDER) | Silver Spring, Maryland | United States | about 9 hours ago
of immunogenicity effects on drug exposure and the investigation of anti-drug antibody (ADA) and neutralizing antibody (NAb) assay characteristics across approved biological products. If selected, you will
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Science About the project This PhD project integrates pharmacoepidemiology, causal inference, and machine learning to study real-world treatment patterns, effectiveness, and safety of monoclonal antibodies
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side effects. Your main tasks will include Isolation of antigen-specific cells from patient samples Generation of recombinant monoclonal antibodies Generation of BCR-transduced cells lines Antibody
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/ Research Associate with strong expertise in antibody technologies and cancer biology to join our dynamic, multidisciplinary research team. Key Responsibilities Perform phage display selection, screening, and
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, causal inference, and machine learning to study real-world treatment patterns, effectiveness, and safety of monoclonal antibodies (mAbs) used in autoimmune, inflammatory, and neurological diseases. Using
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the ADAPT platform, a novel technology that converts antibody CDR-H3 loops into β-hairpin peptide mimetics with antibody-like specificity and improved pharmacokinetic properties. The primary biological focus
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this. Lets change the world. Responsibilities: Develop novel and biopharmaceutical industry leading peptide, protein, antibody and multispecific antibody MS and MS/MS analytical techniques, automation sample