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of Staufen1:RNA complexes in vitro; as well as on gathering detailed information of such assemblies combining light and electron microscopy approaches. Techniques Gene cloning, Protein over-expression
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histological techniques and immunocytochemistry confocal microscopy transmission electron microscopy image analysis using dedicated software (eg Neurolucida for confocal, Neurolucida Explorer, Meta Morph and
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flow cytometry, microscopy and single-cell omics. References Maffia P, Mauro C, Case A, Kemper C. Canonical and non-canonical roles of complement in atherosclerosis. Nat Rev Cardiol. 2024 Apr 10. doi
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microscopy. References MSC-EVs and regenerative medicine: https://pubmed.ncbi.nlm.nih.gov/39547584/ & https://pubmed.ncbi.nlm.nih.gov/35742923/ MSC-EVs in wound healing : https://pubmed.ncbi.nlm.nih.gov
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of histomorphological cancer phenotypes using self-supervised learning on unlabeled, unannotated pathology slides. arXiv. 2023 Albert-László Barabási. Network Science. Cambridge University Press. 2016. http
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seeks to define the life and cell cycles of N. perurans and Perkinsela in detail using light, fluorescence and electron microscopy. In particular, whether the replication of N. perurans and Perkinsela
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effects of collagen IV mutation in cells. Modification of disease development in animal models Techniques used: State of the art imaging techniques including 3-dimensional electron microscopy, confocal
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the Arabidopsis circadian clock. https://pubmed.ncbi.nlm.nih.gov/37897048 Environmental regulation of plant gene expression – the role of ultraviolet light Supervisor: Gareth Jenkins Project description: Light is a
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to understand the fundamental mechanisms of inflammation triggered by permeabilized mitochondria. It will entail a variety of cutting-edge methods including genome-engineering, high-resolution microscopy and in