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multidisciplinary approaches, including human pluripotent stem cell reprogramming and differentiation, CRISPR/Cas9–mediated genome editing, electrophysiology and patch-clamp recordings, advanced imaging techniques
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including single-cell genomics by next-generation sequencing, in situ single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and
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-generation sequencing, in situ single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and study its consequences on tumor
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