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literature: Sandova V et al. IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K delta inhibitor idelalisib. Haematologica. 2021;106(11):2995-2999. https
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targets for therapy. Recommended literature: Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA Biol. 2021 May;18(5):619-632. https://pubmed.ncbi.nlm.nih.gov
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the CXCR4/SDF-1 axis. Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1. PMID: 27480113 Free PMC article Kipps et al. Chronic lymphocytic leukaemia. Nat Rev 2017 https
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and data analysis is desirable. Information about the supervisor: 2 PhD students 2 absolvents Supervisor´s personal webpage https://www.ceitec.eu/dalibor-blazek-ph-d/u25918 Research group info https
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literature: Beekman et al. The reference epigenome and regulatory landscape of chronic lymphocytic leukemia. Nature Medicine 2018 https://pubmed.ncbi.nlm.nih.gov/29785028/ Sun et al. The immune
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regulators and non-coding RNAs. Semin Oncol. 2018 Oct;45(5-6):291-30 https://pubmed.ncbi.nlm.nih.gov/30360879/ Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA
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Axis Regulates Homing Capacity and Tonic AKT Activity in Chronic Lymphocytic Leukemia. Blood 2021 March (epub). https://pubmed.ncbi.nlm.nih.gov/33786575/ Pavlasova G, et al…. Mraz M. Ibrutinib inhibits
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to apply Website https://www.ceitec.eu/designing-coiled-coil-peptides-for-controlled-membrane-fu… Requirements Additional Information Work Location(s) Number of offers available1Company/InstituteCEITEC
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-the-endosomal-barrier-design-principles-of-fusogenic-proteins-for-lipid-vesicles/t11640 Where to apply Website https://www.ceitec.eu/overcoming-the-endosomal-barrier-design-principles-of-fus… Requirements
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. Start date: September 2026 Sign-up link:https://www.ceitec.eu/molecular-insights-into-the-g-quadruplex-helicase-interactome-and-its-functional-implications/t11588 Where to apply Website https