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culture or combinatory approaches, which cannot be analysed in experiments based on conventional culture of CLL/lymphoma primary cells. This project will utilize models developed in the laboratory and will
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these data and we will also analyze primary samples from patients with B cell malignancies. We will identify functions of lncRNAs using CRISPR interference, RNA pulldown experiments, mouse models, and
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literature: Sandova V et al. IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K delta inhibitor idelalisib. Haematologica. 2021;106(11):2995-2999. https
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membranes Excellent track record Good English language – spoken and written Motivated person with collaborative mind set Information about the supervisor: Current group: 9 postdocs, 3 PhD students,2 Master
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group: 9 postdocs, 3 PhD students,2 Master students, 4 technicians Current projects are: National Institute of Virology and Bacteriology, ERC consolidator grant, ERC proof of concept grant, Czech Science