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-in-3d-stem-cell-derived-human-organ-models/t11589 Where to apply Website https://www.ceitec.eu/protein-in-cell-nmr-spectroscopy-in-3d-stem-cell-derived-… Requirements LanguagesENGLISHLevelGood
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/33094664 Mattick JS, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol. 2023 Jun https://pubmed.ncbi.nlm.nih.gov/36596869/ Sharma et al. …Mraz. miR-29
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Boudny, Ph.D. Topic title: Lymphoid microenvironment models and their use to study targeted therapy and resistance in B cell malignancies Annotation: Chronic lymphocytic leukemia (CLL) cells and indolent
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cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs. Leukemia 2024 https
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Research; https://is.muni.cz/auth/osoba/101627 ; More information about the research group: http://mrazlab.ceitec.cz/ Start date: September 2026 Sign-up link:https://www.ceitec.eu/regulation-of-cell
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inhibitors. Blood. 2021;137(18):2481-2494. https://pubmed.ncbi.nlm.nih.gov/33171493/ Pavlasova GM and Mraz M. The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy
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Biol. 2021 May;18(5):619-632. https://pubmed.ncbi.nlm.nih.gov/33094664 Mattick JS, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol. 2023 Jun
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polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing. Molecular Cell 85, 3321–3332.e3325, doi:10.1016/j.molcel.2025.08.002 (2025). Fiedler, M. et al. Head
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets
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into target cells. However, the delivery of mRNA into the cell remains a challenge due to limited endosomal escape. To overcome the endosomal escape barrier, this project aims to computationally design proteins