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and tumor tissue) to determine their immune cell infiltration profiles 3D imaging analyses using fluorescence microscopy techniques (e.g., confocal laser scanning microscopy, light-sheet fluorescence
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HBIGS Heidelberg Biosciences International Graduate School | Heidelberg, Baden W rttemberg | Germany | 6 days ago
and temporal dynamics of phyB PBs relative to nucleosomes using live imaging (phyB and H2B fluorescent lines) and MINFLux super-resolution microscopy at the 10-50 nm scale (using SNAP-tagged phyB and
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responsible for: Analysis of murine tissue samples (heart and tumor tissue) to determine their immune cell infiltration profiles 3D imaging analyses using fluorescence microscopy techniques (e.g., confocal
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investigations. At the subcellular scale, laser scanning confocal fluorescence microscopy (CLSM) and spectral fluorescence lifetime imaging microscopy (spectral FLIM) will enable spatial mapping
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emphasis on techniques used for optical imaging of the human retina. It centers on two-photon fluorescence ophthalmoscopy employing femtosecond laser sources. This technique offers new opportunities
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methodologies including in vivo calcium imaging, optogenetics, electrophysiology, and molecular approaches. The work will be conducted in an international and collaborative research environment, offering
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fluorescence (XRF) and optical reflectance and fluorescence imaging (hyperspectral/multispectral). The primary objective is multimodal unmixing, i.e., estimating pigment abundances at each location under scarce
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, and clinical covariates. Apply these methods to spatial transcriptomics and fluorescence imaging data to gain a more precise understanding of complex biological systems. Research Environment
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these techniques, X-ray fluorescence (XRF) imaging provides detailed information on the distribution of chemical elements across paint layers, giving unique access to pigments, mixtures, and underlying compositions
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. Experience in deep learning, computer vision, or neural network development. Experience with live-cell microscopy, fluorescence microscopy, or analysis of 3D/4D image data. Experience in cell biological