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Field
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. Potential projects include: Developing AI/multimodal models (e.g., integrating single-cell omics, spatial transcriptomics, epigenomics, and proteomics) to simulate virtual neural stem cells or organoids
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, epigenomics, and proteomics) to simulate virtual neural stem cells or organoids. Investigating epigenetic regulation (DNA methylation, histone modifications) in stem cell fate decisions, reprogramming, and
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The position is part of a research project focused on understanding and predicting T-cell receptor recognition of tumor antigens in neural crest–derived cancers, particularly melanoma and neuroblastoma
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of haematopoietic cells are influenced by different microenvironments. To achieve that, we use state-of-the-art single-cell RNA-seq, multiome, and spatial transcriptomics data generation combined with computational
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LevelMaster Degree or equivalent Specific Requirements Biospecimen storage (blood, tissue) Primary cell cultures: methods for cell isolation, passaging, freezing and thawing Protein structure DNA structure and
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lab at Harvard Medical School in Boston, Massachusetts. The Brugge lab has identified populations of breast epithelial cells that carry chromosome copy number alterations (CNAs) that are among the most
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to support tasks 1 and 2 of the project and includes: 1. culturing and maintaining cells under different oxygen levels and assessing their adaptation through monitoring of target proteins by western blot; 2
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regeneration of oral soft and hard tissues. Tasks: - Development of a bioprinting device - Development of bioinks for tissue regeneration - Cell culture assays (viability, proliferation) - Physical-chemical
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of wood formation (CEMACam project). - main mission: The candidate will be tasked with continuing the development of a wood formation simulation model initiated during the project. This 'vertex' model
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an essential process for life. When a cell is at a diseased state, the interaction landscape can drastically change. We develop chemical tools to investigate these interactions to understand health and