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mechanism of CRISPR-associated nucleotide signaling. We also aim to develop innovative tools for fast and sensitive nucleic acid detection and the diagnosis of human disease, using insights gained from our
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-bacterial/microbial-host interactions using molecular, cellular, and tissue-level assays. Designs, performs, and analyzes experiments involving gene perturbation, gene editing (CRISPR/Cas9, RNAi), and gene
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for setting up experimental systems to study type VI CRISPR-Cas defense mechanisms and analyzing collateral RNA damage using RNA-sequencing. KEY DUTIES: 60 % 1. Conduct research on RNA-targeting type VI CRISPR
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culture and molecular biology techniques such as CRISPR gene editing. Certifications/Licenses Required Knowledge, Skills, and Abilities Must be able to follow detailed laboratory instructions. Preferred
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& Biochemistry (MBB) at Rutgers University-New Brunswick. Our lab aims to understand molecular mechanisms of antiphage immunity in bacteria and archaea, focusing on the role and mechanism of CRISPR-associated
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single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and study its consequences on tumor transformation and therapy