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motivated postdoctoral researcher to develop and apply imaging-based and computational approaches to identify predictive nuclear signatures of cell fate. The project combines experimental and quantitative
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and the endoplasmic reticulum. The project will combine approaches in cell biology, biochemistry, and advanced imaging. The candidate will contribute to the development and optimization of experimental
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-assisted mass spectrometry) and cutting-edge instruments (ion mobility coupled with time-of-flight mass spectrometry (TimsTOF), Orbitrap). Your work will be part of major, well-recognized research programs
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Description The selected candidate will join the team studying the signaling pathways responsible for the assembly of nuclear pore complexes during the cell cycle in healthy and diseased cells, in
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, enabling the study of thin batteries. In contrast, the development of operando cells for X-ray photoemission spectroscopy (XPS) studies is still challenging owing to the difficulty of designing a cell
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time days) per year Excellent working conditions (flexible hours, remote work) A company cafeteria offering affordable meals Partial reimbursement of transportation costs (75%) + a sustainable mobility
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meals Partial reimbursement of transportation costs (75%) + a sustainable mobility allowance of up to €300/year A site accessible by public transport + private parking Financial contribution to health
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: interferons alpha, lambda, cross-presentation https://institutcochin.fr/projet-6-cellules-dendritiques-contre-vih-int… . The group is expert in studying interactions between human DC and HIV-infected cell
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in cancer cell signaling. The host team has demonstrated its immunomodulatory role in cutaneous melanoma, and this project aims to evaluate its potential as a therapeutic target. o Perform xenografts
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used will be based on the use of cell-free translation extracts that will allow us to assemble and purify translation initiation complexes on our model messenger RNAs. The composition of these complexes