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on isolated mutations in patients with telomeric disorders Construction of KI cell lines using CRISPR-Cas9 Characterization of the telomeric phenotypes of these KI lines Characterization of the phenotypes
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cloning) and genome-editing methods (TALEN and CRISPR Cas9 in RNP form) in the diatom Phaeodactylum tricornutum. This is a model organism that is produced on an industrial scale. These methodologies have
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