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topic: This position falls within the field of bioenergetics and protein biochemistry. The project aims to study the role of an original extra-membrane structural module involved in the mechanism
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neurological and developmental involvement. Peroxisomes generate high levels of hydrogen peroxide in their matrix but lack typical protein repair systems such as those found in other subcellular compartments
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microscopy, FACS, or high-content screening. -Previous work on cardiovascular biology or muscle-related genetic diseases. -Skills in protein engineering, nanobody development, or synthetic biology. -Knowledge
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genes—either toxic RNA or toxic proteins—responsible for DM, FXPAC, and ALS. The goal of Michał Gdula’s team is to increase the efficacy of therapies for DM1 and DM2 by modulating epigenetic regulation
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biotherapeutics, such as peptides and proteins, into cells - a key hurdle in developing new treatments for cancer and other diseases. This should be accomplished over the course of the next 6 years using
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response under biologically relevant conditions (pH, ionic strength, proteins, oxidative environment). Designing and implementing theranostic approaches, integrating sensing + therapy within the same
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therapeutics by protein design. This project will apply cutting-edge generative AI methods—including protein design, structure–function prediction, and multimodal learning—to develop and optimize a new
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/Biology, sub-area Glycosciences, in the scope of the R & D Project GlycOSELECT - “Targeting a ‘toolbox’ of human microbiome O-Glycan-Selective proteins towards new approaches in cancer research”, with
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of pathological protein aggregation Quantification of α-synuclein pathology Participation in single-cell RNA-seq and proteomic experiments Data analysis, figure preparation, and manuscript drafting Presentation
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lab’s website https://sites.duke.edu/corinnelinardiclab/ . Be You Work Performed · Perform literature reviews to guide research · Design and execution of standard in vitro assays ongoing in the lab