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management will also be developed. References: (1) Nat. Rev. Drug Discov. 2013, 12, 447–464. https://doi.org/10.1038/nrd4010 . (2) Molecules 2020, 25, 2050. https://doi.org/10.3390/molecules25092050 . (3) ACS
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related discipline. A passion for experimental work and capability to develop/apply mathematical modelling techniques will be particularly important for this project. Where to apply Website https
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Factor (PEDF) is required for the development and maintenance of the mammalian retina, but regulation of its abundance and activity remain poorly understood. This PhD project will address a critical gap in
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for airBORNe applications” project (https://newborn-project.eu/) and develop a real-time Multiphysics Digital Twin for such a system accelerating future electric propulsion system development. Motivation
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the global development of targeted therapies. By filling this gap, the project aims to identify and validate promising novel chemical scaffolds to support the creation of potent, specific modulators
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neuroprotective effects. Camptothecin – A clinically relevant anticancer agent targeting Topoisomerase I. In collaboration with Prozomix Ltd. (an industrial leader in enzyme development), this project will
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systems remain too complex for widespread commercial use. This project aims to overcome these barriers by developing a high‑resolution spatial light modulator based on high‑aspect‑ratio silicon pillars
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Application deadline: 31/03/2026 Research theme: Biocatalysis and Protein Engineering Centre for Sustainable Synthesis – BioProcess How to apply: https://www.mib.manchester.ac.uk/research/centres
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Application deadline: 31/03/2026 Research theme: Biocatalysis and Protein Engineering Centre for Sustainable Synthesis – BioProcess How to apply: https://www.mib.manchester.ac.uk/research/centres
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enzyme active site density functional theory (DFT) ‘cluster’ or QM/MM models. The Hough group at Diamond develops methodologies for ambient temperature, time resolved macromolecular crystallography and