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process, modification of the microenvironment components, and integration with state-of-the-art research technologies such as high- and super-resolution microscopy, quantitative image analysis, spatial
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proximity readout. This combination enables sub-100 ps time-of-flight (TOF) precision and millimetre-scale spatial resolution, surpassing the limits of conventional crystal-based scanners. The Xe-LAr offers
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aggregation, mitochondrial dysfunction, and synaptic loss. We will employ among others, spatial transcriptomics, epigenomic profiling, and multielectrode array (MEA) recordings, providing a foundation for in
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