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uncurable. Parkinson's disease is characterized by neuronal inclusions, named Lewy bodies and Lewy neurites, containing aggregated lipids and proteins.The protein alpha-synuclein plays a central role in the
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. The project adopts a systems-oriented and participatory approach, combining policy analysis, co-design, and stakeholder engagement to identify leverage points for accelerating the protein transition
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separation techniques (AF4, SEC) and light-scattering analysis (MALS, DLS); Demonstrated experience in peptide/protein characterization using AF4-MALS, SEC-MALS, and high-resolution mass spectrometry; Strong
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studying folding dynamics of complex proteins in isolation or within a condensate environment. For more information, see: https://www.mashaghilab.org and https://www.universiteitleiden.nl/en/science/drug
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mouse embryonic stem cells to allow for rapid protein depletion, mapping transcriptional effects (RNA-seq, TT-seq, PRO-seq), proximity labeling approaches, ChIP, and the bioinformatic analysis
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scientific environment. Selection Criteria A PhD degree in biochemistry, biotechnology, synthetic biology, microbiology, or a related discipline Practical experience with heterologous protein production