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disrupt gene expression and stress responses. Using cutting-edge molecular and cellular biology approaches, in particular quantitative proteomics, we aim to uncover the mechanisms by which cells repair
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“ubiquitin code”, the ubiquitin system protects us from diseases such as cancer, premature ageing, inflammation and neurodegeneration. We have recently developed a proteomics-based method, named “LinkageID
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of novel mRNP packaging complexes. Applying cellular assays (endogenous CRISPR-tagging, reporter systems, RNA-FISH), proteomics, transcriptomics and high-resolution microscopy we will further dissect the co
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thus regulating cellular glycosylation (Voss et al . (2014), EMBO J), the laboratory has more recently employed state-of-the-art genome editing, tailored cellular models and advanced proteomics and
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biology, including advanced mouse models, epithelial organoid systems, flow cytometry, transcriptomic and proteomic profiling, and spatially resolved analyses. A strong emphasis is placed on integrating
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cell imaging) combined with biochemical and cell biological methods or proteomics. The PhD project is part of the EU-funded doctoral training network “NEUROMECH”, which seeks to characterize the role
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RTG3120 on Biomolecular Condensates ( https://dresdencondensates.org ). Each PhD project is part of an interdisciplinary framework that includes shared training activities, and supervision by
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numerical groups More information on the Junior Research Group can be found under https://tu-dresden.de/mn/physik/itp/das-institut/ag/arbeitsgruppe-quantum-critical-matter?set_language=en . If you have
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, Dr. Manuel Dahmen) Participate in international conferences Unique HDS-LEE graduate school program (including data science courses, soft skill courses and annual retreats) https://www.hds-lee.de
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research with the combined tools of immunology, microbiology, virology, cell biology and molecular biology. For more information, please see https://www.mhh.de/hbrs/zib MD/PhD Molecular Medicine