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pathways, on microbial drug tolerance. The project aims to explore the crucial role of metal ions in the genetic networks that govern drug resistance and tolerance in fungal pathogens, in particular Candida
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of advanced preclinical in vitro and in vitro models inclucing genetic engineering of T cells to address mechanistic and translational questions relevant to clinical application. Your responsibilities
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candidate will join an exciting research program exploring a newly emerging paradigm in immunology: mitochondrial transfer and synthetic organelle therapy. Using newly developed genetically engineered mouse
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our publications here . Our team is at the forefront of bringing autologous cell replacement therapies with CRISPR-edited muscle stem cells towards the clinic (https://www.mdc-berlin.de/news/news/deep
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Helmholtz-Zentrum Dresden-Rossendorf - HZDR - Helmholtz Association | Gorlitz, Sachsen | Germany | 3 months ago
field, such as molecular biology, computational biology, bioinformatics, genetics, computer science, mathematics, or equivalent scientific background # A solid background and motivation to learn more
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. For recent examples of our research, see: Oberbeckmann & Quililan et al. (2024) Nature Genetics DOI: 10.1038/s41588-023-01649-8 Oberbeckmann & Oudelaar (2024) Biochem Soc Trans. DOI: 10.1042/BST20230883
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Stein bei N rnberg, Bayern | Germany | 3 months ago
that packages defined RNA cargos and delivers them to specific cell types. STVs consist of a synthetic protein that is assembled from natural and AI-designed protein domains, along with an engineered fusogenic