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-cell imaging and high-resolution microscopy, you will uncover how these proteins reorganize in response to genotoxic stress and help safeguard the plant genome during development and replication
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, such as TIRF and FRAP, as well as high-resolution approaches, such as correlative light and electron microscopy and expansion microscopy, will be employed. This will lead to better understanding of primary
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, chormatographies, XRDXPS, electron microscopy, and others (link ). Collaborative environment across Nanotechnology Centre, CEET , and CATRIN , with opportunities for international collaboration. Social Insurance
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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 23 days ago
cultured cells, genetics (CRISPR and RNAi), proteomics, and cell biological techniques ranging from microscopy to in vitro biochemical approaches, aiming to elucidate basic principles of membrane protein
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changes and interaction interfaces. Selected plectin–plecstatin complexes will be further analyzed by cryo-electron microscopy to resolve the structural basis of inhibitor binding and its impact on plectin
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of miniplectins in cultured cardiomyocytes. Using advanced fluorescence microscopy and biochemical approaches, the project will assess the ability of mini-plectins to reconstitute cytoskeletal networks, cell–cell
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and molecular dissection of hormone transport/signalling modules reporter lines and quantitative imaging, including confocal microscopy transcriptomics and proteomics with integrative data
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) The subject of the PhD Thesis will be studying polarons in real space by noncontact atomic force microscopy (nc-AFM), focusing on their thermally-, field- and light-induced motion. Further, the growth
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, molecular dynamics, stochastic dynamics, Monte Carlo and analytical methods) and its thorough validation using advanced experimental techniques (such as mass spectrometry, electron microscopy, radiochemistry
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microscopy) Possibility to participate in translational research and collaborate with clinical partners Regular evaluation of PhD thesis progress with the possibility of external consultations Free access