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Department: Lukáš Trantírek Research Group – Central European Institute of Technology Deadline: 31 Mar 2026 Start date: To be negotiated, the sooner the better Job type: full-time Job field
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Environmental science Environmental science » Ecology Technology Researcher Profile Recognised Researcher (R2) Application Deadline 28 Feb 2026 - 22:50 (UTC) Country Czech Republic Type of Contract Permanent Job
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Is the Job related to staff position within a Research Infrastructure? No Offer Description The group of Dr. Pavla Perlíková (https://uoch.vscht.cz/research-groups/perlikova-en ) at the Department
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and functional characterization of mini-plectins engineered plectin variants retaining essential functional domains while being compatible with AAV-mediated gene delivery. The main objective is to
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to targeted therapy. Recommended literature: Hoferkova E, et al…. Mraz M. Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations
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diversity of cell polarization mechanisms evolved. Candidate profile Candidate should have a master’s degree in biology, chemistry, engineering or physics. Experience with any of the following methodologies
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microenvironmental interactions of CLL. We will decipher the molecular functions of these lncRNAs using biochemical and cellular approaches and via a novel lncRNA knock-out mouse model. We have engineered mice
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engineering (CRISPR/Cas), qPCR, and work with reporter lines carry out phenotyping, imaging, and hormone-related assays/tracing contribute to transcriptomic/proteomic experiments and integrative analysis
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of selected plectin domains and engineered variants, followed by biophysical and structural analyses. Hydrogen-deuterium exchange mass spectrometry will be used to identify plecstatin-induced conformational
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DNA Replication, Transcription, and Damage Repair Precision Differentiation Control in Engineered Cell Lines for Scalable Cultivated Meat Production Redox mechanisms of insulin secretion Regulation