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(SHM) is a key process in diversification of antibodies. This process is initiated by cytosine deamination by the activation-induced cytidine deaminase (AID) and completed by error-prone processing
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This research involves mouse studies (surgery and adoptive cell transfer), wet-lab techniques (cell culture, flow cytometry and imaging), and analysis of sequencing and spatial data. The candidate is expected
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with Western blot analysis is considered an advantage. Bioinformatics skills, including basic data processing, statistical analysis, or work with high-throughput or sequencing data, are highly welcome
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-rich cortical poles and associated cortical flows in detached tumour cells, which correlate with metastatic potential. However, these processes lack a rigorous quantitative and three-dimensional
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these processes. In addition, we will explore strategies to restore HSPC function by targeting inflammation-induced vulnerabilities. This work will provide mechanistic insight into how aging-associated inflammation
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biology. More details on the processing of personal data are available on the website: https://www.ibt.cas.cz/en/about-the-institute/official-noticeboard/gdpr/ Where to apply Website https://jobrxiv.org/job
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microscopy, CRISPR, omics approaches (Chip-seq, proteomics), or bioinformatics. How to apply: Cover letter: your motivation to apply for this position and description of your research interests. CV: Highlight
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transformation, or reporter-based imaging basic data analysis skills (R/Python), statistics, or omics/bioinformatics prior experience with hormone biology/plant signalling/transport LanguagesENGLISHLevelGood
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processivity of RNA Polymerase IIat core DNA replication genes. Apart from the C-terminal domain of RNA Polymerase II, other cellular substrates of CDK12 are not known. In this research, we propose using a
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biology. More details on the processing of personal data are available on the website: https://www.ibt.cas.cz/en/about-the-institute/official-noticeboard/gdpr/ Where to apply Website https://www.ibt.cas.cz