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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 12 days ago
the design and enzymatic synthesis of hypermodified xeno-nucleic acids with a combination of modifications at the base, sugar moiety and phosphate linkages. After optimization of the methodology, hypermodified
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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 12 days ago
PROTACs for several kinases, which are validated targets in oncology and in CNS disorders. It will be focused on linker optimization, selection of ligase ligands and specificity for target kinase. Our
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to methanol. In the first phase, we will engineer PSI and redox enzymes for bioconjugation and optimize the self-assembly process. The stoichiometry will be optimized for efficient light driven reduction
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of Organic Chemistry of the University of Chemistry and Technology (UCT) in Prague is looking for a PhD student in Organic/Medicinal Chemistry. Synthesis of antimetastatic compounds targeting actin
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. Graduates gain skills for independent and team work, problem-solving in basic and applied science, and have laboratory and fieldwork experience. They are prepared for a scientific career or expert roles in