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that are abundant in the human genome and overrepresented in evolutionarily conserved and functionally important regions, including the telomeres, centromeres, and promoter regions of (onco)genes. They have been
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to unravel the nucleic acid conformational landscapes. G-quadruplexes (G4) and i-motifs (iM) are paradigmatic non-canonical nucleic acid structures that are abundant in the human genome and overrepresented in
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