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cytochrome P460 containing enzymes. Time resolved and spectroscopically validated crystal structures of enzyme intermediates will be used synergistically with quantum mechanics/molecular mechanics (QM/MM
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) characterisation methods, e.g. crystallography, NMR, IR, Raman, UV/Vis/NIR, and EPR spectroscopies, magnetometry, and quantum chemical calculations; (iii) reactivity studies supported by analytical characterisation
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on precisely defined chemistry, underpinned by measurement of atomic and isotopic composition/distribution with extreme precision e.g. isotopic implants in Quantum Technologies. Investigation of failure
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