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participates in a range of international collaborative projects aimed at fostering multidisciplinary cooperation and contributing to evidence-based decision-making in public health and disease prevention. In
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biological component of the project. The postdoctoral fellow will establish and maintain genetically and fluorescently modified cancer cell models suitable for live-cell mechanobiology, such as reporter
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. The project will also investigate the regulatory roles of individual dual-specificity phosphatases (DUSPs) in the negative modulation of the MAPK/ERK pathway activity in tumour cells. This project builds
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details of virus replication cycles? Join our team! Our research projects focus on determining particle structures and infection mechanisms of human picornaviruses and flaviviruses, as
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genome-wide analysis of the Czech/European population analyzed within the Genome of Europe project, which is currently underway in our laboratory. The successful candidate should: Hold a Ph.D. or its
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of independently planning experiments, prioritizing tasks, resolving project-related issues, and engaging in critical thinking Have exceptional communication and documentation skills Display a high level of
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organoids, deploy CRISPR perturbations and functional assays to map disease pathways, and help establish reproducible 3D testing platforms to evaluate candidate therapeutics across AD, glioblastoma
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of treatment for skeletal dysplasias caused by aberrant FGFR signaling. While our primary interest is the FGF pathway, projects on the entire RTK family are also running in the lab. More about our research: Cell
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, scanning and transmission electron microscopy, nano/micro-CT, mathematical modelling and many others. All of our projects are based on large network of local and international collaborators. This offers