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) Where to apply Website https://www.ceitec.cz/postdoctoral-researcher-in-structural-virology/j659 Requirements Additional Information Work Location(s) Number of offers available1Company/InstituteCEITEC
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that induce fusion between lipid vesicles and endosomes. Using mesoscopic simulations, we will identify the key structural features of proteins with a transmembrane domain that promote membrane fusion
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of leukemias, including chronic lymphocytic leukemia (CLL) and other B-cell malignancies. Much evidence from the latest research shows that CLL cells have an extra deregulated chromatin structure and show an
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
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NMR spectroscopy has emerged as a unique and powerful approach for probing biomolecular structure, dynamics, and interactions directly within living human cells under near-physiological conditions. It
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of these structures, thereby mediating replication, repair, transcription, and DNA damage response through protein barriers. Peptides from helicase motifs can be used to investigate atomistic details of G4-Helicase
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Computational Quantum Chemistry & Spectroscopy About this position: Do you have a passion for understanding the electronic structure of molecules? Join our team! Our research focuses on the relationship between
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Research 43(5):2575-89 (2015) Bösken CA, Farnung L, Hintermair C, Merzel Schachter M, Vogel-Bachmayr K, Blazek D, Anand K, Fisher RP, Eick D, Geyer M. The structure and substrate specificity of human Cdk12
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/s41580-023-00668-x Wang L.; Wang G.; Mao W.; et al. Bioinspired engineering of fusogen and targeting moiety equipped nanovesicles. Nat Commun 2023, 14, 3366, doi: 10.1038/s41467-023-39181-2 Research area
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to targeted therapy. Recommended literature: Hoferkova E, et al…. Mraz M. Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations