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. Our mission is to move beyond descriptive biology and develop predictive, mechanistic models that connect molecular regulation to cellular and systems-level phenotypes. The Laboratory of Computational
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, Biomedical Sciences, Bioengineering, or related fields. Enthusiasm for fundamental science and attention to detail. Motivation to work with an international team of PhD students, postdocs and technicians
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Saelens team. Research Project In this research project you will develop probabilistic deep-learning models that automatically extract biological and statistical knowledge from in vivo perturbational omics
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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. These coordinated hormonal activities influence not only the rate of cell division but also the duration and dynamics of each phase of the cell cycle. With the advent of advanced technologies, such as single-cell
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of the cell cycle. With the advent of advanced technologies, such as single-cell genomics and live-cell imaging, we can now explore hormone regulation at unprecedented single-cell resolution. Using these tools
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role in membrane remodeling. It also aims to deepen the mechanistic understanding of solute transport in ion channels and transporters of medical relevance. We apply state of the art methods
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, proteomics, microscopy, structural biology, technology development, and bioinformatics at VIB-UAntwerp Center for Molecular Neurology (https://cmn.sites.vib.be/ ), at VIB (https://vib.be/ ), and at UBirmingham