-
, transcription, mRNA processing, RNA polymerase II, cancer, genomics, proteomics, substrates, kinase inhibitors. Funding of the PhD candidate: Project EXPRO (2023-2027) In the academic year 2026/27 the net
-
. Annotation: Protein-DNA interactions are critical in cellular processes and genetic instability-related conditions, particularly involving G-quadruplexes (G4) and their complementary C-rich sequences (i-Motif
-
receptor (BCR) signaling and B-T cell interactions. Human genome contains large numbers of lncRNAs that can regulate various physiological cellular processes or contribute to the onset or aggressiveness
-
Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets
-
Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Overcoming the Endosomal Barrier: Design Principles of Fusogenic Proteins for Lipid Vesicles Annotation: Cancer remains one of the leading causes
-
Sep 13. PMID: 25080849 Review. Research area: Cancer biology Keywords: lymphoma, CLL, migration, microenvironment, co-culture Funding for the PhD candidate: In the academic year 2026/27 the net
-
. 2012; 24(6):634-9. https://pubmed.ncbi.nlm.nih.gov/22960555/ Research area: Cancer biology Keywords:CLL, microenvironment, CD20, BTK/PI3K inhibitors Funding for the PhD candidate: In the academic year
-
the PhD student using technics such as genome editing (CRISPR), RNA sequencing, use of primary samples, functional studies with various in vitro and in vivo mouse models. The research is also relevant
-
), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
-
novel regulators of the B cell survival, proliferation and crosstalk with other immune cells. The PhD student will further investigate this using techniques such as genome editing (CRISPR), RNA sequencing